CRISPR Immune Cell Screens
Identify disease-relevant targets for therapeutic needs with CRISPR screening services in primary human immune cells.
Gene editing CRISPR screens can uncover genetic factors that govern function and behavior in T cell research.
CRISPR screens allow for the systematic knockout of individual genes in T cells, enabling the identification of genes essential for T cell development, activation, differentiation, and response to antigens.
By understanding the genes involved, the underlying mechanisms of T cell-mediated immune responses, autoimmune diseases, and immunotherapies can be better understood.
Utilize a high-performance all-in-one CRISPR Knockout vector system that achieves precision by completely silencing gene expression. This provides an optimal window to observe both phenotypic and functional effects.
Arrayed T cell CRISPR KO screens
Arrayed screening approach employing CRISPR-Cas9 gene-editing technology to systematically knockout specific genes within T cells on a well-to-well basis for complex phenotypic endpoints.
Arrayed screening approach employing CRISPR-Cas9 gene-editing technology to systematically knockout specific genes within T cells on a well-to-well basis for complex phenotypic endpoints.
Pooled T cell CRISPR KO screens
Pooled screening approach employing CRISPR-Cas9 gene-editing technology to knockout specific genes with T cells for analyzing the impact of gene loss at the population level.
Pooled screening approach employing CRISPR-Cas9 gene-editing technology to knockout specific genes with T cells for analyzing the impact of gene loss at the population level.
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